Selected recent publications

On cerebral cortex development

Saulnier A, Keruzore M, De Clercq S, Bar I, Moers V, Magnani D, Walcher T, Filippis C, Kricha S, Parlier D, Viviani L, Matson CK, Nakagawa Y, Theil T, Götz M, Mallamaci A, Marine JC, Zarkower D, Bellefroid EJ. (2013). The Doublesex Homolog Dmrt5 is Required for the Development of the Caudomedial Cerebral Cortex in Mammals. Cereb. Cortex, 23, 2552-2567.

Young FI, Keruzore M, Nan X, Gennet N, Bellefroid EJ, Li M. (2017). The doublesex-related Dmrta2 safeguards neural progenitor maintenance involves transcriptional regulation of Hes1. Proc Natl Acad Sci U S A,  114, 5599-5607.

Muralidharan B, Keruzore M, Pradhan S, Roy B, Shetty A, Kinare V, D’souza L, Maheshwari U, Karmodiya K, Suresh A, Galande S, Bellefroid E.J, Tole S (2017). Dmrt5, a novel neurogenic factor, reciprocally regulates Lhx2 to control the neuron-glia cell fate switch in the developing hippocampus. J. of Neurosci. 37, 11245-11254.

De Clercq S, Keruzore M, Desmaris E, Pollart C, Assimacopoulos S, Preillon J, Ascenzo S, Matson CK, Lee M, Nan X, Li M, Nakagawa Y, Hochepied T, Zarkower D, Grove EA, Bellefroid EJ. (2018). Dmrt5 together with Dmrt3 directly controls hippocampus development and neocortical area map formation. Cereb. Cortex 28, 493-509.

Desmaris, E., Keruzore, M., Saulnier, A., Ratie, L., Assimacopoulos, S., De Clercq, S., Nan, X., Roychoudhury, K., Kricha, S., Lingner, T., Henningfeld, K. A., Zarkower, D., Mallamaci, A., Theil, T., Campbell, K., Pieler, T., Li, M., Grove, E., & Bellefroid, E. (2018). DMRT5, DMRT3 and EMX2 cooperatively block Gsx2 at the pallium-subpallium boundary to maintain cortical identity in dorsal telencephalic progenitors. J. Neurosci. 38, 9105-9121.

Ratié L, Desmaris E, García-Moreno F, Hoerder-Suabedissen A, Kelman A, Theil T, Bellefroid EJ, Molnár Z. (2019). Loss of Dmrt5 affects the fiormation of the subplate and early corticogenesis. Cereb. Cortex Cpii: bhz310. doi: 10.1093/cercor/bhz310. [Epub ahead of print]

On sensory neurogenesis

Nagy, V., Cole, T., Van Campenhout, C., Khoung, T.M., Leung, C., Vermeiren, S., Novatchkova, M., Wenzel, D., Cikes, D., Polyansky, A.A., Kozieradzki, I., Meixner, A., Bellefroid, E.J., Neely, G.G., Penninger, J.M. (2015). The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception. Cell Cycle 14, 1799-1808.

Thélie, A., Desiderio, S., Hanotel, J., Quigley, I., Van Driessche, B., Rodary A., Borromeo, M.D., Kricha, S., Lahaye, F., Croce, J., Cerda-Moya, G., Ordono Fernandez, J., Bolle, B., Lewis, K., Sander, M., Pierani, A., Schubert, M., Johnson, J.E., Kintner, C., Pieler, T., Van Lint, C., Henningfeld, K.A., J., Bellefroid. E.J., Van Campenhout C. (2015). Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus. Development, 142, 3416-3428.

Desiderio S, Vermeiren S, Van Campenhout C, Kricha S,  Malki E, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld K, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ. (2019). Prdm12 directs nociceptive sensory neuron development by regulating the expression of the NGF receptor TrkA. Cell Rep. 26, 3522-3536.

For a full reference list click here

Bellefroid Lab